Are you considering your first aesthetic treatment but feeling a bit overwhelmed? You’re not
alone! The world of cosmetic enhancements, while incredibly exciting, can be confusing!
(Especially with so many options available!)
Neuromodulators are designed to help reduce the appearance of fine lines and wrinkles by
treating the muscles beneath the skin to provide you with a more refreshed, youthful look! In this
guide, we’ll break down the differences between Botox, Dysport, Xeomin, and Jeuveau in
simple terms, so you can feel confident in your decision.
What are Neuromodulators?
Neuromodulators like Botox, Dysport, Xeomin, and Jeuveau are injectable treatments that
temporarily relax the facial muscles responsible for creating dynamic wrinkles—those pesky
lines that appear when you smile, frown, or raise your eyebrows. These treatments can be
effective for areas like crow's feet, forehead lines, and frown lines, lip flip, facial slimming,
necklace bands, downturned corners of the mouth, pores and texture, and jawline definition.
In the hands of a skilled aesthetic provider neuromodulator treatments will help you look like a
more youthful and refreshed version of yourself, not fake or frozen!
Botox: The Classic Choice
Botox is probably the most well-known neuromodulator. It was the first neuromodulator
approved by the FDA for cosmetic use, and it remains a popular choice for many patients! Botox
is also notorious for the “Botox Glow” which creates a beautiful glow in treated areas!
Why People Love Botox:
● Research: If you love research, Botox has tons! The research shows that Botox is safe
and effective for both cosmetic and therapeutic treatments.
● Customizable: Your injector can tailor the treatment to your specific needs adjusting
dosing and placement to help you achieve your desired goals!
What to Expect:
● Onset: Results may begin to be noticed in 3-7 days, but can take up to 14 days to kick
in with full effect being seen at 3 weeks!
● Duration: Your tox will be tightest at 2 weeks, begin to soften at 4 weeks, and then you
will see a gradual return to movement. Results typically last about 3 months with
adequate dosing.
● Side Effects: Some people may experience mild bruising or headaches, sensations of
heaviness or tightness, but these are usually temporary.
Dysport: The Fast-Acting Option
If you’re looking for quicker results, Dysport might be the best choice for you! This
neuromodulator has a different formulation with a lower molecular weight than Botox or Jeuveau
allowing for quicker spread. This makes it perfect for larger areas and allows it to take effect
more quickly! It also contains 2-3 times the active ingredient compared to its competitors like
Botox, Xeomin, and Jeuveau!
Benefits of Dysport:
● Quick Results: Many clients see effects within 24 to 48 hours with full effects being
seen and evaluated at 3 weeks!
● Wider Spread: It can cover larger treatment areas, making it ideal for certain facial
zones.
● More Active Ingredient: Dysport has 2-3 times the active ingredient as compared to its
competitor!
● More Natural Looking: Dysport provides soft movement without static lines and doesn’t
create the same shine/glow seen with Botox treatments.
● Customizable: Dosing and placement can be tailored to meet your aesthetic
needs/goals by your provider!
What to Expect:
● Duration: Results generally last around 3-4 months with appropriate dosing.
● Side Effects: Similar to Botox, with potential for mild bruising and headache.
Xeomin: The “Pure Tox”
Xeomin stands out because it contains no added proteins, which may reduce the risk of
developing resistance over time. It is also extremely flexible and light so it is a great treatment
option for things like hyperhidrosis (excessive sweating) and for those wanting a very flexible
result!
Why Choose Xeomin?
● Fewer Additives: This makes it a great option for those who might have had issues with
other neuromodulators or who have allergies or reactions to the proteins in other popular
neuromodulators.
● Lighter: The lack of a stabilizing protein makes it the lightest of all of the
neuromodulators! This leads to greater spread and makes it a wonderful option for larger
areas and treatment for hyperhidrosis (excessive sweating.)
What to Expect:
● Onset: Effects can take a bit longer to kick in compared to Botox or Dysport and full
effects are seen at 3 weeks. Due to its flexible nature Xeomin may wear off more
quickly than other tox options with the same dosage.
● Side Effects: Generally mild, similar to the other options discussed.
Jeuveau: The New Kid On The Block
Jeuveau is the newest addition to the neuromodulator family and is specifically designed for
aesthetic purposes, meaning it doesn’t have clinical indications for therapeutic use at this time.
This is also the only other neuromodulator with the same molecular weight as Botox, with similar
onset, duration, and results!
What Makes Jeuveau Unique?
● Focus on Aesthetics: Its research and development specifically targets those seeking
cosmetic improvements.
● Similar Longevity: Results last about 3 to 4 months, like Botox.
● Precision: The increased molecular weight helps to provide for less spread and more
precision than lighter neuromodulator options such as Dysport and Xeomin.
● Great for Resistant Patients: Juveau is a great alternative for patients who want the
results of Botox or Dysport, but have become resistant to the stabilizing proteins in those
products over time.
What to Expect:
● Onset: Effects typically appear within 3 to 7 days with full effects showing at 3 weeks.
Some patients report that it kicks in for them sooner than Botox.
● Side Effects: Similar to other neuromodulators, but still relatively new on the market so
more research is ongoing at this time.
Key Differences at a Glance
Neuromodulator Onset of Results Duration Our Clinical Observations
Botox 3-7 days, full
results at 2-3
weeks
3-4 months Best for a “tight” result, also provides
the “Botox Glow” to treated areas.
The largest molecular weight of any
toxin, can lead to a sensation of
“heaviness” in some patients.
Dysport 24-48 hours, full
results at 2-3
weeks
3-4 months Faster onset, 3 times the active
ingredient as Botox, softer more
natural looking results, longer
duration for many patients.
Xeomin 3-7 days, full
results at 2-3
weeks
3-4 months No added proteins, very light and
flexible, duration is slightly shorter in
clinical observations with equivalent
dosing.
Jeuveau 3-7 days, full
results at 2-3
weeks
3-4 months Quick onset, very comparable
duration to Botox and Dysport, a
great option for those who have
become resistant to other treatments
over time.
Which neuromodulator is right for you?
With several options available, the best choice for you depends on your specific aesthetic goals,
anatomy, and lifestyle. It’s essential to consult with a qualified professional who specializes in
delivery of aesthetic neuromodulator treatments to determine which will be the best option for
you! Providers can also use different neuromodulators in different areas to create a truly
customized approach to your aesthetic goals!
What’s Next?
If you’re ready to schedule a consultation for your first neuromodulator treatment, here are a few
steps to take:
1. Research: Read up on each option to understand what might work best for you.
a. Botox
b. Dysport
c. Xeomin
d. Jeuveau
2. Consult: Schedule a consultation with one of our highly qualified providers to discuss
your goals and treatment options here!
3. Ask Questions: Don’t hesitate to ask about the procedure, recovery, and any potential
side effects! Our jobs as aesthetic providers is to provide education to help you be as
well informed as possible. You should always feel like a collaborative partner with your
provider along the way of your aesthetic journey!
Conclusion
Stepping into the world of aesthetic treatments can be exciting yet daunting. By understanding
the differences between Botox, Dysport, Xeomin, and Jeuveau, you’re taking a significant step
toward achieving your desired look. Remember, the best results come from a tailored approach,
so seek professional guidance to ensure you feel confident and comfortable throughout your
journey.
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